产品货号：
Z22148
中文名称：
NMDAR2B/GRIN2B抗体
英文名称：
Anti-NMDAR2B/GRIN2B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NMDAR2B/GRIN2B Antibody |
| 指标别名 | GluN2B;GRIN2B;hNR3;NMDAR2B;NMDAR2B/GRIN2B;NR2B;NR3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM(Intracellular),Direct ELISA |
| 基因名称 | GRIN2B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NMDAR2B/GRIN2B recombinant protein (Position:F1132-I1480). |
| 实际分子量 | 160KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily.The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate.The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system.The NMDA receptors are heterotetramers of seven genetically encoded,differentially expressed subunits including NR1 (GRIN1),NR2 (GRIN2A,GRIN2B,GRIN2C,or GRIN2D) and NR3 (GRIN3A or GRIN3B).The early expression of this gene in development suggests a role in brain development,circuit formation,synaptic plasticity,and cellular migration and differentiation.Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder,attention deficit hyperactivity disorder,epilepsy,and schizophrenia. |
| Uniprot ID | Q13224 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | glutamate receptor,ionotropic,N-methyl D-aspartate 2B |
| 蛋白名全称 | Glutamate receptor ionotropic,NMDA 2B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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